The orthogonal design method of table L9 (34) was adopted to construct nine different feeding models for Chinese mitten crabs (Eriocheir sinensis) based on four factors, such as the coverage of aquatic plants, the input of live snail, the ratio of animal based feed to total feed and different feed casting patterns, and their three levels. 540 two-year old Chinese mitten crabs with initial body weight of 9.67±0.47 g were fed in 27 separate pens (6 m×5 m×2.5 m) in the raising areas of east Taihu lake for 240 days following these feeding models with three replicates, and the effects of these feeding models on growth of Chinese mitten crab and their relation to its incidence of hepatopancreas albinism were comparatively analyzed. The results showed that different feeding models exerted significant effects on its growth and hepatopancreas albinism incidence. Among these feeding models, model IV produced the best raising results and brought the lowest incidence rate. The results from variance analysis indicated that the effects of the four factors on growth and albinism incidence were listed in the order of importance as: the coverage of aquatic plants> the ratio of animal based feed to total feed>the feed casting patterns> the input of live snail. A statistical regression analysis was conducted based on the four factors, together with parameters of albinism incidence, weight gain, fullness, capture rate, and feed conversion efficiency. The results confirmed that the coverage of aquatic plants, the ratio of animal based feed to total feed, and the feed casting patterns had close relations to the albinism incidence and growth of Chinese mitten crabs. It is suggested that the feeding model suitable for the raising of Chinese mitten crabs be characterized as follows: the coverage of aquatic plants was 73.95%, the animal based feed accounted for 56.15%～62.22% of total, the feed was given during whole growth and developmental stages and in the amount of 7.5%～5.0% of the crab weight, the amount of live snail input was 5578.05 kg·(hm2)-1. Key words: Eriocheir sinensis; growth; feeding model; hepatopancreas albinism