The olfactory organs development of blunt snout bream was investigated using histological and morphological methods. The results revealed that the olfactory organs of blunt snout bream were positioned on the back and in front of the eyes. The olfactory epithelium (OE) was oval-shaped near the base of the olfactory cavity. The olfactory placodes were parallelly arranged in the cranio-caudal direction. There were concave marks on the olfactory fossa’s periphery when fish were hatching out. Afterwards, an elongated olfactory placode was formed in the olfactory fossa’s core. The arrangement of the primary olfactory placodes of the unilateral OE were from loose to tight with blunt snout bream growth. The height and number of the olfactory placodes, as well as the overall surface area of the OE gradually expanded and stabilized in the adult stage. qRT-PCR were used to studied the expression patterns of representative ORs. The results showed that ORs expression differed in different stages and tissues of blunt snout bream. ORs Beta-2, 9, 10, and 11 were highly expressed during several phases of embryonic development, including the blastocyst stage, blastopore closure stage and olfactory plate stage (P<0.01). Beta-2, 9, 10, 11 and Epsilon-7 were weekly expressed at from 3 to 15 dpf, in the larval and juvenile stages, but highly expressed at 30 to 60 dpf (P<0.01). Beta-2, 10, 11 and Epsilon-10, 13 were strongly expressed in the OE of 4 periods from juvenile stage to adult (including 3, 6, 12 and 24-month-old) (P<0.05). Beta-2, 9, 10, 11 and Epsilon-7, 10, 13 were also highly expressed in the OB (olfactory bulb) in 3-month-old blunt snout bream (P<0.01), but not expressed in 6 to 24-month-old stage. Beta-2, 11 expression levels were low in the brain of 4 periods (P<0.05). These findings will provide new insights into the molecular mechanism of ORs in fish feeding regulation, and deepen the cognition of fish olfactory recognition.